Yup. It's treated as perfectly normal. And no one looks down on Otae for being a hostess, or thinks it's weird that Shinpachi's sister can kick his butt (he gets picked on for coming across as a wuss at times-which he isn't-not for having a sister who can beat him up with her pinky) and when Kagura is pointed out for being weird, it's because she's an alien with alien habits, not because she's a girl who can easily destroy city blocks. Ditto with Sacchan being an assassin.